Medication: Modafinil
Brands: Provigil, Alertec, Modavigil, Modalert, Modiodal, Modafinilo, Movigil, Modvigil, Forcilin, Resotyl, Wakelert
Tablet Strength: 200 mg, 100 mg
Price: from $0.72 per pill
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Modafinil (Provigil)

Modafinil is a medicine taken to promote wakefulness. It works by altering neurotransmitters, natural chemicals in the brain. This medication is prescribed to treat excessive sleepiness caused by such conditions as narcolepsy, sleep apnea, and shift work sleep disorder. Similar to amphetamines, Modafinil stimulates the brain to promote wakefulness, but its exact mechanism of action is not clearly known. It may work by increasing the dopamine amount in the brain, decreasing its reuptake into the nerves. Originally, this medication was developed in France in the late 1970s. Modafinil was approved to promote wakefulness by the FDA in 1998.

Important Information and Precautions

You shouldn’t start this treatment if you have any possible allergies or skin rash. The intake of Modafinil may cause severe skin reactions that must be treated in the hospital. Stop using it and get emergency medical help once you develop such symptoms as:

  • Hives and skin rash;
  • Skin peeling and blistering;
  • Difficulty swallowing and breathing;
  • Mouth sores and fever;
  • Dark urine and swelling;
  • Yellow eyes and skin.

Before taking Modafinil, inform doctors if you have such health conditions as chest pain, kidney and liver problems, psychosis, other mental illnesses, drug addiction, alcoholism, high blood pressure, and heart diseases. Its use affects the central nervous system, and this medicine may impair your normal reactions and thinking, so be careful when driving and doing other things that require your full alertness. Avoid other activities that can be dangerous until you know how Modafinil affects your wakefulness level.

It’s not known if this medication causes any harm to unborn babies or passes into breast milk, but it can make birth control pills less effective. Modafinil is not intended to be taken by anyone who is less than 17 years old. Avoid drinking any alcoholic beverages when taking it, or you may end up with increased side effects.

How to Take It Correctly

Take this medication as prescribed by your physician and written on the label. Don’t use it in higher or lower doses and for longer than needed. Modafinil is a habit-forming medicine, so you shouldn’t give it to other people. Take your dose every morning to prevent daytime sleepiness or about 1 hour before starting the next working shift if you want to treat work-time sleeping disorders. It’s allowed to take regular doses with and without food, but your treatment shouldn’t be longer than 12 weeks.

Mild and Severe Side Effects

Like other drugs, the use of Modafinil may cause certain side effects. Go to the hospital right after experiencing such signs of allergic reactions as difficulty breathing, hives, and swelling. Stop taking this medicine and call your doctor if you have the following troubling symptoms:

  • Mouth sores and swelling in legs;
  • Skin rash, blistering, peeling, and hives;
  • Shortness of breath and trouble swallowing;
  • Fever and jaundice;
  • Urine changes.

Get medical help once you develop such severe side effects as:

  • Suicidal actions or thoughts;
  • Anxiety and depression;
  • Unusual behaviors and thoughts;
  • Hallucinations and aggression;
  • Trouble breathing and chest pain;
  • Being more talkative and active than usual;
  • Uneven heartbeats and skin rash signs.

The intake of Modafinil may cause mild side effects, including:

  • Back pain and stuffy nose;
  • Feeling anxious and nervous;
  • Dizziness and headaches;
  • Upset stomach and insomnia;
  • Diarrhea and nausea.

If any of them become troublesome or persistent, call your doctor at once.

Unwanted Drug Interactions

Drug interactions are dangerous and should be avoided because they may change the way Modafinil works while increasing a possible risk of experiencing severe side effects. Some of the most common pharmaceutical products that may interact with this medicine include such street drugs as ecstasy and methamphetamine.

Besides, Modafinil may reduce the effectiveness of some hormonal birth control methods, including pills. Its intake may speed up the removal of specific meds from the human body, thus, affecting the way they work. Don’t combine Modafinil with such affected drugs as bosutinib, axitinib, and some meds that treat chronic hepatitis C.

Some medications contain the ingredients that can raise your blood pressure and heart rates, so you should be careful when taking them along with Modafinil to be on a safe side. Caffeine may increase side effects caused by this medicine, so that you need to avoid drinking different beverages that contain it, eating a lot of chocolate, and taking supplements with caffeine. The chemical formula of Modafinil is quite similar to armodafinil, so these drugs shouldn’t be taken together.